Greg Downey & other: 2008

Monday 8 September 2008

Persons of the Week: Cancer Survivors

Jason Connelly has metastatic melanoma. Ellen Rigby has stage-four breast cancer. And Terry Barter has multiple myeloma. Not long agone each of these noncurable cancers would have meant a death sentence. But advances in treatment ar not only keeping each patient alive, they are allowing the three to live full lives.

Jason Connelly

Six years ago, Jason Connelly was diagnosed with early-stage melanoma and had a small ontogenesis removed from his back. Doctors at M.D. Anderson Cancer Center in Houston said his cancer was gone. But four years later it returned as thousands of tiny tumors in his abdomen. For most citizenry the genus Cancer would have killed them.

"When you're in that situation, you're faced with deuce choices," Jason recalls. "You can either deal with it and attack it, or you can let it kill you."

He chose to attack it, opting for a toxic treatment called high-dose interleukin-2. It is so potentially deadly it has to be given in the intensive care unit of a hospital. After six months of what he describes as sin, Jason's genus Cancer was gone.

Watch "World News with Charles Gibson" TONIGHT at 6:30 p.m. ET for the full story.

"When you make up that transition between being sick and not existence sick, it's like beingness on a train going 80 miles an hr that all of a sudden stops. And you go fast-flying off the train," Jason said of finding out he was in remission.

Jason started a blog called Fighting in Texas, where he shares his experiences with cancer.

When his genus Cancer returned, Jason made a promise to his then 2-year-old logos: "I am going to live to see him get marital." Jacob is now four and the reason Jason gets up every morning.

Ellen Rigby

In 2001, when Ellen Rigby base out she had chest cancer, it had already spread to her liver. But the type of cancer she has, oestrogen receptor positive and HER-2 positive bosom cancer, gave her doctors treatment options beyond traditional chemotherapy and radiation.

"The key with metastatic disease is to superintend the disease and balance the efficacy of the treatment with the quality of your life. The treatment can be very toxic," explained Ellen.

The toxic treatment is a case of chemotherapy, which Ellen has been taking on and off for six-spot years. But right now her doctors at Memorial Sloan Kettering Cancer Center in New York are giving her a internal secretion therapy, Faslodex, and a targeted therapy called Herceptin. Both have virtually no side effects.

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Friday 29 August 2008

Bath Researchers Study How Cancer Cells Come Unstuck

�Scientists in the Department of Biology & Biochemistry at the University of Bath stimulate started a three year study into the junctions that hold cells together, giving insight into how cancer cells can break off and spread to other parts of the body.

Cancer affects one in three people at some point in their lives, with about cancer deaths being caused by the development of secondary tumours in early parts of the body. This research, funded by leading aesculapian charity Cancer Research UK, could help scientists better understand what causes cancer to spreading and english hawthorn suggest new ways it could be treated in the future.

Normal cells are held together by junctions on the cell surface, but in some cancers these junctions are lost. This makes the cancerous cells more likely to break off and spread head tumours to other parts of the body. Dr Andrew Chalmers and Dr Paul Whitley, both lecturers from the Department of Biology & Biochemistry, are studying how a chemical group of proteins called ESCRTs are involved in the loss of these junctions in kidney and bowel cells.

"ESCRTs are like the recycling units of the cell; they oversee the constant uptake, break down and replenishing of junctions on the cell surface," explained Dr Chalmers.

"In a cancer cadre where ESCRTs are discredited, the junctions may not be restored properly; this can cause cells to separate and migrate to form secondary tumours in other parts of the body.

"Previous studies have shown a link between ESCRTs and the loss of junctions in cells of fruit flies, so we want to see whether this is also true in humans."

During this trey year jut out, the researchers plan to block ESCRTs in cells grown in the science lab to watch the personal effects on the junctions. They will besides be looking at whether mutations of ESCRTs are more uncouth in sure types of cancer.

Dr Paul Whitley added: "This work should evidence us more than about the role of ESCRTs in cancer and provide possible new targets for therapy in the future."

BATH UNIVERSITY

Wessex House

Bath

BA2 7AY
http://www.bath.ac.uk

More information

Tuesday 19 August 2008

Mp3 music: Bobby Orlando

Artist: Bobby Orlando: mp3 download

   Genre(s):

Blues
Electronic
Country

Bobby Orlando's discography:

The Best of the musica 80s Vol 2

Year: 1987

Tracks: 12

The Best of the musica 80's Vol 5

Year:

Tracks: 13

The Best of the musica 80's Vol 4

Year:

Tracks: 12

The Best of the Best of the musica80s Vol 1

Year:

Tracks: 12

Producer Bobby Orlando became a legend in the '80s through a mass of disco music and Hi-NRG records released on his independent mark, O Records. The son of a Westchester, NY, school teacher, Orlando boxed true kO'd of high school and listened to Alice Cooper and T. Rex. He off down a greco-Roman medicine scholarship, instead performing Johnny Thunder-style guitar in teenager sparkle bands. Swept up by disco, Orlando engineered "Dancin'" by Todd Forester in 1977. The call featured the galloping sea bass part contrast developed by synth-phenom Giorgio Moroder, wHO Orlando strove to emulate throughout his life history. Orlando as well highly-developed a womb-to-tomb fascination with the studio beau idealistic of ABBA. In 1980, Orlando masterminded the 1st-class mail Lyn Todd album, before setting up O Records. The number one releases, "Just a Gigolo" by Barbie & the Kens and "Change of Life" by I Spy, made Billboard's dance chart. As disco died, Orlando unflinchingly overflowing the market place with beat-heavy blasts. Some, like Roni Griffith's "Desire" and "Take a Chance on Me" by Waterfront Home, became golf golf club hits. Also in 1980, Divine came to Orlando for his production expertness, and the mate unleashed a string of notoriously successful singles. Orlando so devised the Flirts, a figurehead trinity of revolving beauties to perform his songs. Orlando's Nunzio Brocheno Productions as well produced Lisa Lisa & Cult Jam and Full Force. This subway rage social movement was dubbed Hi-NRG and light-emitting diode Smash Hits writer and Pet Shop Boy Neil Tennant to seek out Orlando. Orlando launched the career of the British twosome, including an early rendering of "West End Girls." The Pet Shop Boys left for EMI and worldwide achiever. Hurt by the want of gratitude from his volume stable of artists, Orlando gentle phased out of his music empire. He returned to his law studies and finished a rule book called Darwin Destroyed, refuting the possibility of development. In the '90s, he began some other pronounce, Reputation Records.

Saturday 9 August 2008

Alejandra Guzman

Artist: Alejandra Guzman

   Genre(s):
Rock
   Dance
   Other
   Pop

Discography:

Indeleble

Year: 2006
Tracks: 11

Lipstick

Year: 2004
Tracks: 11

En vivo

Year: 2003
Tracks: 20

Agresivamente tuya

Year: 2002
Tracks: 16

Soy

Year: 2001
Tracks: 9

Serie Platino: 20 Exitos

Year: 2000
Tracks: 19

Algo Natural

Year: 1999
Tracks: 14

Eternamente Bella

Year: 1997
Tracks: 10

Cambio De Piel

Year: 1996
Tracks: 10

Enorme

Year: 1994
Tracks: 10

Al Borde De La Locura

Year: 1994
Tracks: 14

Libre

Year: 1993
Tracks: 11

Flor De Papel

Year: 1991
Tracks: 10

Dame tu amor

Year: 1989
Tracks: 8

Bye mama

Year: 1988
Tracks: 10

La Guzman [CASSETTE]

Year:
Tracks: 16

Singer/actress Alejandra Guzman was born into a playing family, the girl of Mexican actress Silvia Pinal and Mexican rock star Enrique Guzman. Appropriately sufficiency for a famous person child, she made her first TV visual aspect when she was hardly two months old. She spent her childhood preparing to be a long-familiar performing creative person in her own veracious, tattle, terpsichore and traveling with her mom's theatrical company. Following her mother's wishes, she didn't pursue a perfoming calling in full until she ruined school; after she gradatory, the 17 year-old Guzman appeared in a production of Mame with her mother. From that day, she knew she wanted to be a singer.

Afterward teaming up with producer Miguel Blasco, Guzman recorded her debut album Pass Mama, which was number one in Mexico within years of its vent. She released albums nearly yearly afterwards her debut and enjoyed a big, enthusiastic fanbase throughout Latin America. Though Guzman encountered some personal problems in the mid and recent '90s, including a stay in rehab and a divorce, she brought her life history full circle in 1998 by coming into court onstage with her mother once more, this time in a production of Romany, and released her twelfth album Algo Natural in 1999.

Chris Rock

Tuesday 1 July 2008

Metope

Artist: Metope

   Genre(s):
Electronic

Discography:

Kobol

Year: 2005
Tracks: 8

Monday 30 June 2008

Acid King

Artist: Acid King

   Genre(s):
Metal: Doom
   Metal: Death,Black

Discography:

III

Year: 2005
Tracks: 7

Free (With Mystick Krewe Of Clearlight)

Year: 2001
Tracks: 6

Busse Woods

Year: 1999
Tracks: 6

San Francisco's lapidator rock candy band Acid King formed in 1993. Singer/guitarist Lori Crover, bassist Peter Lucas and drummer Joey Osbourne started performing local shows that twelvemonth with likeminded bands such as the Melvins, Hawkwind and the Obsessed. The mathematical group released their self-titled debut EP the next twelvemonth on Sympathy For the Record Industry, which they followed with the 1995 uncut Zoroaster. While touring to sustenance the album, Lucas resign the isthmus and was replaced by Dan Southwick, besides a member of Altamont, the side project of Melvins drummer (as well as Lori's married man) Dale Crover. Acid King returned in 1997 with the Down With The Crown EP, which was released on Frank Kozik's Man's Ruin mark. The next twelvemonth Southwick returned to Altamont and Acid King found a newfangled bassist in Brian Hill; the new card released Busse Woods in 1999.

Funky Technicians

Pearl Jam - Pearl Jam Join Fight Against Insurance Companies

Rockers PEARL JAM are backing a campaign to raise money for patients fighting health insurance companies for payouts.

A pre-concert party is being held in Hartford, Connecticut on Friday (27Jun08), ahead of the band's gig there - organised by Advocacy for Patients with Chronic Illness head Jennifer Jaff.

Pearl Jam were introduced to the cause by lead guitarist Mike MCCready, who has suffered bowel disorder Crohn's Disease for 25 years.

Jaff also suffers the disease and is currently fighting her own battle with an insurance company to cover the cost of her treatment.

MCCready tells the Hartford Courant newspaper, "Jennifer Jaff is one of the best advocates for patients I have ever seen. It's super-important for her to fight against the insurance companies that will deny people any kind of coverage for their pre-existing conditions. The work she does is justified, and I just love it.

"We live in the greatest country in the world, and I have lived here my entire life, but we need to invest our money back into things that look at a broader scope, not just things that are going to make us money. If people are going to die because some legislation didn't go through, that, to me, is abhorrent. That's not what America means to me."

See Also

Lil Wayne Makes Lyrical Attack On Sharpton

Rapper LIL WAYNE has lashed out at U.S. civil rights leader REVEREND AL SHARPTON in the lyrics to a new song, branding the minister a "nobody".
On the track Misunderstood from his new album Tha Carter III, the Lollipop hitmaker takes aim at the race activist, rapping: "You are nobody to me/You're just another Don King (boxing promoter) with a perm/Just a little more political/And that just means you a little more un-human/Than us humans... F**k Al Sharpton and anyone like him."
But Sharpton insists he takes no offence to the slur, reported by AllHipHop.com - because he claims Lil Wayne has no credibility as a musician.
He says, "While some of the rappers don't like the fact that Rev. Sharpton has been leading marches against the degradation of women in music, a Gallup (opinion) poll released last week revealed that Reverend Sharpton has a 50 per cent approval rate among African-Americans.
"So why dignify a response to one rap artist who doesn't even say anything substantive?"

Barry Obrien

Artist: Barry Obrien

   Genre(s):
Other

Discography:

Spark

Year: 2004
Tracks: 4

Alanis Morissette - Flavors of Entanglement

Love Spirals Downwards

Artist: Love Spirals Downwards

   Genre(s):
New Age

Discography:

Temporal

Year: 2000
Tracks: 13

Flux

Year: 1998
Tracks: 9

Sideways Forest

Year: 1997
Tracks: 3

Ever

Year: 1996
Tracks: 11

Ardor

Year: 1995
Tracks: 11

Idylls

Year: 1992
Tracks: 13

Love Spirals Downward (L.S.D. for inadequate) formed in Los Angeles in 1991 when guitarist, keyboardist, and composer Ryan Lum asked Suzanne Perry to record vocals o'er some music he had written. The positive results lED to a recorded demonstration, and by late 1992, the duet released their showtime album, Idylls, on the ethereal Projekt pronounce. Their debut maintained a strong Cocteau Twins vibration, but they differed from that grouping by virtue of Perry's discrete vocal trend and a dreamier, folksier sound that manifested itself on subsequent releases, each of which suffer shown L.S.D. more strongly defining their personal fashion, lento only gradually denudation off the processing and becoming more acoustically based. In fact, their sporadic North American shows give birth in the main featured Lum on acoustic guitar and Perry tattle. E'er shows them experimenting with modern electronica, also evidenced by an ethereal drum'n'bass tune performed at the 1997 Projekt Festival in Chicago. Magnetic field followed in 1998. Throughout their career, the duo get kept up a strong following among the Goth specify, fifty-fifty though their audiences are far more varied than that. Ethereal tribe is the topper fashion to line them, for they accommodate neither the image nor the coloured climate of the Gothic writing style, although their occasional melancholiac edge does explain the association. By the new millennium, Lum started the Lovespirals project with singer/songwriter Anji Bee on vocals. Lovespirals issued Windblown Kiss in summer 2002.

Sunday 29 June 2008

New Face For Wisteria Lane

A new face will be appearing on Wisteria Lane in the new season of television’s ‘Desperate Housewives’, with Neal McDonough joining the cast of the hit show.
The former star of ‘Boomtown’ is making the movie into the famous street, playing a potential romantic encounter for Nicolette Sheridan’s character Edie Britt.
McDonough’s casting also squashes rumors that Sheridan was set to leave the top rating series at the end of last season.
Additionally, The Hollywood Reporter says that Gale Harold will also join the show as Ken, the man seen kissing Teri Hatcher’s character Susan Meyer at the end of the last season’s finale.
Photo courtesy of TriStar Pictures.

Country music's "Idol" moves to NBC

PASADENA, Calif. — John Rich, half of the country-music sensation Big & Rich, achieved stardom the old-fashioned way: He earned it. The Texas native, with pal Kenny Alphin, spent years playing jam sessions at Nashville bars and at fairs across the country before they landed a record deal.

He didn't have a show like NBC's "Nashville Star" to give his career an instant boost. In five previous seasons on the USA Network, the "American Idol"-style competition show for country singers has launched the careers of Buddy Jewel, Miranda Lambert and Chris Young.

The show moves to NBC for its sixth season starting tonight. Contestants will be eliminated weekly until a winner is named. The prize is a recording contract and a chance to perform at the Summer Olympic Games in Beijing.

Country music doesn't come and go in a flash, says Rich, 34, one of the show's judges. He predicts the winner of this round of competition will have a career that lasts for decades.

"It's not over when you hit 30 years old in country music. You're just getting started."

Singer Jewel and songwriter Jeffrey Steele join Rich as judges, with Billy Ray Cyrus as host.

See Also

John Mayer covers George Harrison and Duffy at Glastonbury

John Mayer shocked the gathered Pyramid Stage crowd at this afternoon's Glastonbury festival by pulling out covers a plenty.

Wearing white t shirt and black jeans Mayer and his band took to the stage at 3.30pm (BST).

Clutching a gold guitar the singer American songwriter didn't waste any time and launched into an hour's bluesathon which saw the main stage crowd get bigger with each track.

After finishing opening song 'Vultures' Mayer then swapped his guitar and backed by a band member playing some maracas, a saxophonist and trumpeter started next track � 'I Don't Trust Myself With Loving You'.

The last part of the song saw Mayer showing off his guitar playing talents pulling faces with each strum.

Before starting the next track in a nod to the now deceased legend Mayer said: "This is one of my favourite George Harrison songs."

The crowd then cheered as Mayer started his rendition of the classic track, 'My Sweet Lord', with people singing along word for word.

With the song finished Mayer then swapped back to his electric guitar and smiled at the crowd.

He then asked the Pyramid Stage group: "You all having a good time today? Thanks for letting us steal the stage for a bit. I was watching the festival on TV last night and there really is something about the European festival vibe that's great. I've finally figured it out and I don't want to leave now. "

The crowd all shouted up at him and Mayer and band started their next song which saw Mayer playing elongated blues riff solos while biting his lip.

Mayer teased the crowd saying: "We'd like to play for you now a smash hit of a blues song."

Mayer and band then covered Duffy's 'Mercy' joined by a mini horn section again which received a huge applause.

The band then continued with tracks including 'Belief', 'Stitched Up', which Mayer wrote with jazz legend and another cover 'Crossroads' by Cream.

continued the thank the ever growing gathered crowd throughout the set � obviously chuffed that so many people had come out to see him.
As the set ended Mayer thanked his fans one last time saying: "Thanks so much for listening from the front to the back."

The band then left the stage to a large applause.

John Mayer played:
'Vultures'
'I Don't Trust Myself With Loving You'
'My Sweet Lord'
'Waiting On The World To Change'
'Mercy'
'Heavier Things'
'Belief'
'Stitched Up'
'Crossroads'
'Gravity'

Keep up with all the action from Glastonbury this weekend (June 27-29) as it happens on NME.COM. For news, pictures and blogs keep checking the NME.COM's Glastonbury Festival page. Plus make sure you get next week's issue of NME � on UK newsstands from July 2 � for the ultimate Glastonbury review